Get ahead of cancer with the Cancerguard™ test

Peace of mind starts with a single blood test that helps detect cancer, even aggressive and hard-to-find types, before symptoms appear.

  • For ages 50-84 with no known cancer in the last 3 years1
  • Helps detect cancer types behind at least 80% of diagnoses — including 6 of the deadliest1
  • Can detect cancers with no screening options that cause ~70% of cancer deaths1
  • Detected 1 in 3 early stage cancers in a clinical study1
  • $689, HSA/FSA eligible*
Request Cancerguard
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Get ahead of cancer with the Cancerguard™ test

Peace of mind starts with a single blood test that helps detect cancer, even aggressive and hard-to-find types, before symptoms appear.

  • For ages 50-84 with no known cancer in the last 3 years1
  • Helps detect cancer types behind at least 80% of diagnoses — including 6 of the deadliest1
  • Can detect cancers with no screening options that cause ~70% of cancer deaths1
  • Detected 1 in 3 early stage cancers in a clinical study1
  • $689, HSA/FSA eligible*
Request Cancerguard

Many cancers are detected too late to be effectively treated

Cancerguard is designed to complement standard cancer screening, and give you the early insight you need to make more confident decisions.
~70% of cancer deaths occur in cancers without screening options1
Only 4 out of dozens of cancers currently have screening guidelines2
Only 1 in 7 cancers are detected through screening, that’s just 14%‡,4

Helps find it early

Give yourself the best chance to fight cancer by finding it in its early stages — when it's easier to treat.

42%

reduction in stage IV cancer incidence with supplemental Cancerguard testing†

Helps find the most aggressive

Catch the deadliest and most aggressive cancers that often aren't diagnosed until symptoms appear.1

6+

Cancerguard helps detect hard-to-find cancer, including 6 of the deadliest cancers1

Helps find more cancers

Many cancers don’t have screening options. With a simple blood draw, Cancerguard helps detect multiple types of cancer that make up at least 80% of all cancer diagnoses in the US1 including:

  • Lung and bronchus
  • Breast‖
  • Colon and rectum
  • Uterus
  • Kidney
  • Head and neck
  • Pancreas
  • Prostate‖
  • Cervix
  • Bladder and urinary
  • Stomach
  • Esophagus
  • Liver and bile duct
  • Ovary
  • Anus
  • Thyroid
  • Vulva
  • Small intestine
  • Non-Hodgkins lymphoma
  • Testes

‖ The Cancerguard test is not indicated for breast and prostate cancer screening, however it may detect these cancers. The performance characteristics of additional cancer types that may be detected by the test is unknown. This test is not a replacement for existing recommended cancer screening or diagnostic modalities for cancer.

Is Cancerguard right for you?

Peace of mind starts with early detection

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Designed for those most likely to benefit.

Cancer status
No known cancer in the last 3 years
Recommended age
50-84
Cancer status
No known cancer in the last 3 years
Recommended age
50-84

Who else can benefit from expanded screening?

A woman walking down the street wearing headphones and looking at her smartphone.

Anyone at increased risk

If you have increased risk factors such as smoking or obesity.
A grandparent sits outside with their son and grandchildren.

A family history of cancer

When cancer hits close to home, you have even more reason to screen.
Two sisters with grey hair smiling and looking out a sunny window.

In remission for 3+ years

Cancerguard can detect cancers that standard screenings might miss.

Searching for signals of cancer in your cells

  • Cancerguard detects signals of cancer within the body.
  • Helps provide insight before symptoms ever appear.
  • Our multiple biomarker approach looks at protein and DNA to detect cancer earlier — when it matters most.
Get actionable results

Negative or positive. That’s it.

Cancer can be intimidating — understanding your results doesn’t have to be. No jargon, just clear insight to help you move forward with confidence.
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Two weeks to get results

Results typically take just two weeks for our lab to process.
Report icon.

Easy to understand

Your report is specifically designed to help you and your doctor determine your next steps.7
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Follow up care support

If your results are positive, we'll help guide you through next steps, and may reimburse you for follow-up imaging or other scans if you qualify.

Committed to detecting cancer earlier

A team of Exact Sciences technicians wearing white lab coats and safety goggles.
We launched the Cologuard® test in 2014 — and have been a pioneer in cancer screening innovation for over two decades.
We’ve partnered with respected institutions since 2016 and in most of our major studies of Multi-Cancer Early Detection (MCED) technology.8
With over two decades of experience helping millions navigate life-changing cancer diagnoses, Exact Sciences is redefining cancer screening with Multi-Cancer Early Detection (MCED) testing.

Peace of mind is closer than you think

HSA/FSA eligible
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A collage of images showing confident, smiling people.

Footnotes and references

  1. $689 amount reflects self-pay price. FSA/HSA/HRA programs may be a resource you could use to pay as well.
  2. 42% expected reduction in late-stage cancer incidence over a 10-year timeframe with Cancerguard™ compared to standard of care.3
  3. Limitations: Based on modeling data derived from numerous sources including self-reported surveys. Includes assumptions on detectability of certain cancer types. Does not include all cancer types or screening methods.
  4. The percentages shown represent the delta between five year survival rates of local and distant diagnoses.
  5. Check with HSA/FSA administrator to determine eligibility

  1. Cancerguard Clinician Brochure. Exact Sciences Corporation. Madison, WI.
  2. Data on file. Calculated cancers without USPSTF recommended screening tests. 2025. Medical Affairs, Exact Sciences, Madison, WI.
  3. Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A. Cancer statistics, 2025. CA Cancer. J Clin. 2025;75(1):10‐45
  4. NORC at the University of Chicago. (2022). Percent of Cancers Detected by Screening in the U.S.‡
  5. American Cancer Society. Cancer Facts & Figures 2025. Atlanta: American Cancer Society; 2025. Last Revised: January 16, 2025
  6. American Cancer Society. Symptoms of Esophageal Cancer | Esophagus Cancer Signs. Published March 20, 2020
  7. Exact Sciences. Cancerguard™ Care Navigation Guide. Published 2025. Accessed July 23, 2025.
  8. Lennon AM, Buchanan AH, Kinde I, et al. Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention. Science. 2020;369(6499)